HIPK3 and osteosarcoma: Circ‐0000285 is another circRNA generated from HIPK3. Zhang et al found that overexpression of circ‐0000285 increased the colony‐forming ability, proliferation and migration of osteosarcoma cells in vitro and accelerated the growth of osteosarcoma xenografts in vivo whereas knockdown of circ‐0000285 produced the opposite effects.