Although, thus far, mutations or SNPs of p32/C1qbp have found to associate with progressive external ophthalmoplegia or exacerbations of myopathy and influenza infection in human, respectively (Feichtinger et al., 2017) (Chatzopoulou et al., 2018), further studies might reveal genetic anomalies of p32/C1qbp in mitochondrial disorders exhibiting anemia and B-lymphopenia with currently unidentified pathologies. This evidence concerns the gene C1QBP and anemia (phenotype).