PTH and Hypocalcemia: To determine whether NPSP795 can rectify the hypocalcemia of Nuf mice (Table 1), a submaximal dose (25 mg/kg) was administered by s.c. bolus injection, and plasma concentrations of adjusted‐calcium, phosphate, PTH, urea, and creatinine measured at 0, 0.5, 1, 3, and 6 hours postdose in WT and Casr+/Nuf mice, and at 0, 0.5, and 3 hours in CasrNuf/Nuf mice (Fig. 3).