TM6SF2 and metabolic dysfunction-associated steatotic liver disease: Other genetic variants associated with paediatric NAFLD risk include SNPs in the Transmembrane 6 Superfamily Member 2 (TM6SF2) gene,58 which results in impaired lipid mobilization via very‐low‐density lipoprotein (VLDL)59; and the glucokinase regulatory protein (GCKR) gene,60 which results in the activation hepatic glucose uptake, blocks fatty acid oxidation, and promotes lipogenesis.61