LGALS3 and Hepatic fibrosis: M2BPGi, which is mainly produced by hepatic stellate cells and may interact with Mac‐2 positive cells such as macrophages to induce biological activity, is a reliable marker for assessing liver fibrosis in patients with viral hepatitis and other fibrotic liver diseases, such as primary biliary cholangitis, biliary atresia, autoimmune hepatitis, and NAFLD.14, 15