The addition of cytochrome c had none or a slight effect on the intactness of mitochondrial outer membrane after a short (20 min and 30 min) ischemia/reperfusion period, whereas after 40 min and 60 min of ischemia/reperfusion, it stimulated the state 3 respiration rate with both substrates, glutamate/malate, and succinate, but with succinate, it was much more obvious (respiration rate increased two and four times, respectively, p < 0.05, Tables 1 and 2). Here, CYCS is linked to ischemia.