Laser ablation is often accompanied by corneal edema, anterior chamber reaction, intraocular hemorrhage, cataract formation, and intraocular pressure changes, while the anti-VEGF therapy is complicated by damage of healthy vessels, potential side effects on neurons, rapid vascular regrowth upon interrupting the VEGF blockade, and nonresponse in some patients [7–9]. This evidence concerns the gene VEGFA and corneal edema.