In this study, four lncRNAs, AC099850.3, LUCAT1, ZFPM2-AS1, and AC009005.1, were found to be significantly associated with autophagy-related genes and the survival of HCC patients and were selected to develop the prognostic model according to the TCGA and HADb databases. The gene discussed is ZFPM2; the disease is hepatocellular carcinoma.