No significant differences in the expressions of claudin 1 (HF-100 p = 0.45, HF-150 p = 0.07) or occludin (HF-100 p = 0.17, HF-150 p = 0.47) were found between weeks 8 and 0 in both groups (Figures 6G,H). This evidence concerns the gene OCLN and hydrops fetalis.