KCNA3 and torsades de pointes: Women have a higher predisposition to genetic mutations that potentiate TdP and have a higher risk of TdP with Long QT syndrome (LQTS) type 1 and type 2, caused by mutations in potassium channel gene KCNQ1 (KvLQT1) and mutations in potassium channel gene KCNH2 (also known as hERG), respectively (19, 20).