The activity of nSR100 was shown to be important in the inclusion of microexons in the transcripts of EIF4G component of the transcription initiation complex, in MEF2C transcription factor transcripts, and in transcripts shown to be aberrant in autism including ANK2, NBEA (neurobeachin), NRXN2 (neurexin 2), and in SHANK 1 (SH3 and multiple ankyrin repeat domains 1). This evidence concerns the gene NRXN2 and autism.