Schaffer et al. (2019) noted that hypomyelinating leukodystrophies may also result from defects in proteins involved in the charging of TRNAS, aminoacyl-tRNA synthetase complex interacting multifunctional protein 1 (AIMP1) and aminoacyl-tRNA synthetase complex interacting multifunctional protein 2 (AIMP2). This evidence concerns the gene AIMP1 and leukodystrophy.