ATR and neoplasm: The result of the database analysis is supported by a recent study by Cheng’s group, which reported that the analysis of tumor samples from patients with non-small cell lung cancer treated with anti-PD-1/PD-L1 antibody using next-generation sequencing revealed that patients with DDR mutation (the most commonly mutated DDRs were ATM, ATR, BRCA2, POLQ, and RAD50 in the analysis) exhibited high TMB.