SIRT6 and breast cancer: Some studies have shown that long non-coding RNA NONHSAT101069, SIRT6 protein, transforming growth factor (TGF-β), fibroblast growth factor receptor (FGFR) 4 rs1966265 and FGFR2 rs2981578 get involved in anthracycline resistance in breast cancer (20–23), as well as other factors.