CD8A and Epstein-Barr virus infection: Similarly, EBV micro-RNAs help the virus to evade CD8 T cell immune responses in co-culture by inhibiting MHC class I antigen processing and presentation, reducing IFNγ production by CD8+ T cells and suppression of EBNA1 antigen gene expression, thereby potentially contributing to reduction of CD8+ T cell immune surveillance and establishment of life long EBV infection (96).