CD8A and Epstein-Barr virus infection: A comparison between responses to immediate early, early and late lytic EBV protein epitopes in activated CD8+ T cells derived from patients with IM and memory CD8+ T cells from patients with chronic EBV showed that patients with IM had most prominent responses to immediate early and early lytic epitopes, while long term EBV carriers have demonstrated highest cytotoxic T cell responces to late lytic viral proteins, suggesting that anti-viral immune responses are modulated in different EBV infection stages (84).