YTHDF2 and metastatic malignant neoplasm in the lymph nodes: In stratified analysis (Figures 1B–O), lower YTHDF2 expression was significantly associated with poor prognosis of ccRCC patients with lower TNM stage (stage I–II, P = 0.013); elder age (>61, P = 0.005); non-distant metastasis (P = 0.002); late T stage (T3+T4, P = 0.043); non-lymph node metastasis (P < 0.001); female gender (P = 0.001); and higher histological grades (G3+G4, P = 0.011).