GSEA indicated that multiple cancer signaling pathways (mTOR pathway, GSK3 pathway, EIF4 pathway, CHREBP2 pathway, MET pathway, NFAT pathway, FAS pathway, EDG1 pathway, AKT pathway, and CTCF pathway) were differentially enriched in YTHDF2 increased expression phenotype. This evidence concerns the gene YTHDF2 and cancer.