Specifically, NFE2L2 appeared to be a risk factor in 4 cancer types: ACC (P = 0.0016, HR = 1.03), LGG (P < 0.0001, HR = 1.03), PAAD (P = 0.0076, HR = 1.01), and UCS (P = 0.00019, HR = 1.02). The gene discussed is NFE2L2; the disease is adrenal cortex carcinoma.