NFE2L2 and adrenal cortex carcinoma: Subsequently, we investigated the relationship between NFE2L2 expression and DFI and found that increased NFE2L2 expression was correlated with poor prognosis in ACC (P = 0.0021, HR = 1.05) and PAAD (P = 0.026, HR = 1.03) but with favorable prognosis in OV (P = 0.0099, HR = 0.99) and PRAD (P = 0.00044, HR = 0.98) (Figure 5).