AA was tested in three different PD models: PD transgenic Drosophila flies, where it caused significant improvement in climbing ability and prolonged the lifespan—effects attributed to AA antioxidant properties; rotenone-induced damage in SH-SY5Y cells, where it protected mitochondria from oxidative stress and apoptosis; and in an isolated mitochondria model, where AA promoted membrane integrity and ATP production against the decline in membrane potential induced by α-synuclein. This evidence concerns the gene SNCA and Parkinson disease.