This well-known NADPH oxidase inhibitor was used by Hou et al. [271] to treat mice induced to PD by pesticide exposure (paraquat and maneb), causing significant improvement of mouse learning and memory deficits, effects associated with the inhibition of signal transducers and activators of transcription 1 (STAT1) and NF-ĸB pathways. The gene discussed is STAT1; the disease is Parkinson disease.