In contrast with a study by Chen et al. [1], we found no significant association between DAS28 and IL-2; however, IL-6, IL-17A, and IL-17A/IL-10 increased from the healthy controls to RA patients with low DAS28 to patients with moderate DAS28 scores, suggesting that IL-6, IL-17A, and the Th17/Treg axis could be the key drivers of the progression of RA among the study population. This evidence concerns the gene IL6 and rheumatoid arthritis.