IFN-γ (0.30 (0.13-0.55) vs. 0.00 (0.00-0.62), p = 0.032), TNF-α (0.20 (0.00-0.43) vs. 0.00 (0.00-0.02), p < 0.0001), IL-4 (0.49 (0.17-0.80) vs. 0.00 (0.00-0.64), p = 0.006), IL-6 (1.06 (0.63-1.43) vs. 0.00 (0.00-0.98), p < 0.0001), IL-10 (1.10 (0.58-1.49) vs. 0.01 (0.00-1.44), p = 0.045), IL-17A (0.29 (0.14-0.65) vs. 0.00 (0.00-0.02), p < 0.0001), IL-6/IL-4 (1.80 (0.67-4.84) vs. 1.00 (0.49-1.99), p = 0.018), and IL-17/IL-10 (0.23 (0.11-0.71) vs. 0.00 (0.00-0.39), p = 0.007) were significantly higher in RA cases compared to the healthy controls (Figure 1). This evidence concerns the gene IL4 and rheumatoid arthritis.