FGF2 and Parkinson disease: In our proteomic analysis, we observed a Rab8b and Rab31 enrichment in EVs after FGF2 treatment of hippocampal neurons and, therefore, applied network and functional analysis methods to investigate the interactome of Rabs and their possible association to PD pathology having EV Rab8b and Rab31 as guiding forerunners (Figures 1, 2A).