The ROC curves of CEP55, IFI44, NCF4, and TCIRG1 in the TCGA database are displayed and show good efficacy in diagnosing ccRCC with AUC of 0.934, 0.881, 0.924, and 0.913 respectively (Supplementary Figure S6A). The gene discussed is TCIRG1; the disease is nonpapillary renal cell carcinoma.