The altered expression level of hub SFs has been reported in multiple types of cancer, such as YBX1 (Rossner et al., 2016; Chen et al., 2019), SART1 (Ishida et al., 2000; Sasatomi et al., 2000; Yutani et al., 2001), SNRPE (Tamura et al., 2007; Jia et al., 2011), and SF3B4 (Liu et al., 2018). The gene discussed is SART1; the disease is cancer.