It is possible that the expression of these functionally antagonistic genes is an artifact of the process of surface-staining and FACS-sorting the cells, but we favor the hypothesis that the CD32-high cells in the human tissue to which we have access are more strongly affected by the presence of cancer elsewhere in the same liver lobe, and this accounts for the strong expression of these immunologically active genes. This evidence concerns the gene FCGR2B and cancer.