FLNA and infection: As seen in Figures 4A–D, a gradual decrease in FLNA protein and mRNA level was observed as the multiplicity of infection increased, with FLNA protein levels found to be significantly down-regulated by approximately 80% upon infection at MOI = 5 and FLNA mRNA levels found to be significantly down-regulated at MOI = 1, 2, and 5 by approximately 1.