The pig is an interesting case, as its ACE2 protein was both predicted (Wan et al., 2020) and demonstrated experimentally (Zhou et al., 2020) to bind SARS-CoV-2 spike protein; however SARS-CoV-2 neither replicated nor caused disease in pigs after experimental infection (Schlottau et al., 2020; Shi et al., 2020). The gene discussed is ACE2; the disease is infection.