Notably, Shiga toxins 1 and 2 (Stx1 and Stx2) encoded by stx1 and stx2 can result in gastrointestinal symptoms, such as diarrhea and hemorrhagic colitis, and may also progress to a hemolytic uremic syndrome, a severe sequela of this infection (Saeedi et al., 2017). This evidence concerns the gene STX1A and infection.