More ovulatory disorders (73.4% vs. 0.5%; P<0.001), higher baseline LH level (5.8 vs. 3.6 IU/L; P<0.001) and lower FSH level (5.1 vs. 5.6 IU/L; P<0.001) were found in the PCOS group compared with the control group. The gene discussed is PLOD1; the disease is polycystic ovary syndrome.