Our results are consistent with a previous small cohort study, which showed that PA patients had higher glucose levels; in that study, hyperglycemia could not be explained by decreased insulin sensitivity because the insulin levels and the HOMA-IR index were similar in both groups, whereas it could be explained by a lower β-cell function due to aldosterone excess, as HOMA-β index was lower in PA patents than in EH patients (17). The gene discussed is INS; the disease is Hyperglycemia.