DNMT3B and major depressive disorder: According to a postmortem study from suicide patients with MDD, there was no significant change of DNMT3A expression in the prefrontal cortex, amygdala, and paraventricular nucleus of hypothalamus, but the DNMT3B expressions were increased in the prefrontal cortex and paraventricular nucleus and decreased in amygdala of patients compared to healthy controls (6).