The circulating levels of MIF are elevated in T2D (Yabunaka et al., 2000), Type 1 Diabetes (Bojunga et al., 2003; Ismail et al., 2016) and a number of other autoimmune diseases (Ayoub et al., 2008; Vincent et al., 2019). This evidence concerns the gene MIF and type 1 diabetes mellitus.