CXCL8 and myocarditis: Similarly, digoxin blocked the lipopolysaccharide-stimulated secretion of IL-6, IL-8, and TNF-α from mononuclear cells (Ihenetu et al., 2008), but promoted the expression of TNF-α and IL-6 in the heart of mice with myocarditis (Matsumori et al., 1999).