CRP and cancer: Different systemic inflammatory indicators including NLR, LMR, CRP, and Alb have been analyzed in several malignant tumors with poor outcome and low therapeutic response (Lee et al., 2006; Stotz et al., 2014; Gu et al., 2015; Koh et al., 2015; Kim et al., 2016; Jing et al., 2017; Rajendran et al., 2018).