IL1B and chronic obstructive pulmonary disease: MitoVit-E suppressed the sepsi-induced peripheral and myocardial production of cytokines, including IL-1β, improving mitochondrial function and heart activity, while Mito-Q restored mitochondrial function in chronic obstructive pulmonary disease (COPD) patients, reducing inflammation and IL-8 release in preclinical studies (Zang et al., 2012; Wiegman et al., 2015).