Loss of cavin3 expression has been observed in several human malignancies including lung cancer (Xu et al., 2001), gastric cancer (Lee et al., 2008), colorectal cancer (Moutinho et al., 2014), ovarian cancer (Tong et al., 2010), and BC (Xu et al., 2001; Bai et al., 2012). This evidence concerns the gene CAVIN3 and colorectal cancer.