In ‘X’ axis of the cluster 7 different associated pathways (JAK-STAT signalling pathway, cytokine-mediated signalling pathway, positive regulation of tyrosine phosphorylation of STAT3 protein, IL6 type cytokine signal transduction, Herpes simplex infection, negative regulation of cell proliferation and insulin resistance) are shown (Fig. 4b). The gene discussed is INS; the disease is herpes simplex infectious disease.