Children with a lifetime history of eczema were more likely than their counterparts without eczema to report a father’s [2.19 (1.56–3.09)] and mother’s history of allergic disease [1.94 (1.42–2.67)]; residing in the city at birth [1.55 (0.91–2.63)]; the highest reported frequency of de-worming in last 12 months [1.63 (1.10–2.43)]; and the highest reported frequency of ‘trucks passing on the street near their home’ currently [1.94 (1.14–3.32)], but there were no differences for SPT, asIgE and total IgE (Table 4). The gene discussed is IGHE; the disease is allergic disease.