In patients whose metabolic control has deteriorated quickly, in whom other non‐insulin treatments were ineffective and who had low or normal body weight or experienced weight loss, the possibility of type 1 diabetes mellitus or latent autoimmune diabetes in adults (LADA) as an underlying cause of metabolic decompensation should be considered and insulin started promptly.2, 4. This evidence concerns the gene INS and type 1 diabetes mellitus.