TET2 and neoplasm: As shown in Fig. 6a, b, TET2 (WT) cells caused smaller tumor masses than the mock vector control after 6 weeks of observation (SMMC-7721/FGFR3∆7–9/TET2 (WT), 562.8 ± 332.15 mm3; SMMC-7721/FGFR3∆7–9/vector, 1604.6 ± 500.2 mm3; P < 0.05).