The LBOs also have the potential to model aspects of respiratory viral infection in the human parenchyma, including infection of ATII cells with MERS-CoV and SARS-CoV-1 and 2 [17]. LBO sections stained positive for the SARS-CoV-2 entry receptors ACE2 and TMPRSS2 (suppl. The gene discussed is TMPRSS2; the disease is infection.