IDH1 and astrocytoma (excluding glioblastoma): When comparing overall T-cell infiltration (CD3+) in primary glioma with and without the most common IDH1(R132H) mutation (Table 1 and Table S3), we observed a significantly higher T-cell infiltration in IDHwt compared to IDHmut astrocytoma (Figure S2a), which is in accordance with current literature [6].