The SMILE study, which included 650 men, 18–70-years-old, with stable CAD, who had an MI event at least 6 months before the study, and 646 healthy men, revealed no clear association between ADAMTS-13 and the vWF plasma levels, measured more than 6 months after the onset of MI [72]. The gene discussed is VWF; the disease is coronary artery disorder.