Significant differences between groups were registered only in CD8+ at invasive margins (IM) of PTs (group A vs. group B: 166.7 ± 16.6 vs. 533.3 ± 88.1; p = 0.0150) and in GrzB+ cells into tumor cores (TC) of MTs (group A vs. group B: 58.6 + 8.6 vs. 27.6 + 2.7; p = 0.0270). This evidence concerns the gene CD8A and neoplasm.