An in vivo study found that dopaminergic transporter SLC6A3 mRNA levels are significantly lower in the brains of seizure-naïve genetically epilepsy-prone rats [61], suggesting that the nine-copy allele of the 40 bp repeat polymorphism in DAT gene modulates neuronal network excitability and contributes to the epileptogenesis of IAE. Here, SLC6A3 is linked to epilepsy.