IGHE and Alzheimer disease: The expression levels of the pro-inflammatory cytokines were significantly decreased in the MCMC group compared to those in the DNCB group and Naïve group (Figure 4A–E), and one of the universal markers of AD, the serum IgE levels measured with ELISA, were also significantly lower in the MCMC group than the DNCB group and Naïve group (Figure 4F).