GJB2 and GJB6 single nucleotide variants (SNVs) and deletions del(GJB6-D13S1830) and del(GJB6-D13S1854) were studied in 600 NSHL Argentinean patients by Sanger Sequencing and GAP-PCR, respectively. The gene discussed is GJB6; the disease is nodular sclerosis classical Hodgkin lymphoma.