IL6R and cardiovascular disorder: Biomarker [8,[21], [22], [23]] and human genetic [24], [25], [26] results with similar strength to those of this study have formed part of the evidence basis for efforts to re-purpose IL-6R inhibitory therapy in cardiovascular disease (e.g. clinicaltrials.gov registered trials number NCT03004703, NCT01491074, or NCT02419937).