INS and hyperandrogenism: However, its phenotype is accompanied by a much wider range of reproductive (ovulatory dysfunction, polycystic ovarian morphology, infertility), endocrine (hyperandrogenism, disturbed gonadotropins level) and metabolic (glucose metabolism, insulin sensitivity, lipid profile) features (Fauser et al. 2012; Krul-Poel et al. 2018).