Given that elevated GABAARN input is largely to the proximal dendrite of GnRH neurons in PCOS-like animals [12, 14] and the high degree of NPY co-expression in GABAARN neurons [31], we aimed to investigate whether the NPY/AgRP-specific subpopulation of GABAARN neurons is remodeled in the PNA mouse model of PCOS. This evidence concerns the gene GNRH1 and polycystic ovary syndrome.