KNG1 and neuropathic pain: Given the established role of BK in determination of spike width in DRG (Scholz et al., 1998; Zhang X. L. et al., 2012; Noh et al., 2019) and action potential propagation (Gemes et al., 2013), the implications for increased neurotransmitter release in the spinal dorsal horn (Furukawa et al., 2008), a recent report that overexpression of BK increased mechanical threshold in a rodent neuropathic pain model (Zhang et al., 2018), and the availability of a BK activator (Chen et al., 2009a), these channels would seem at least as viable a target as Kv7 and A-channels for therapeutic intervention.