Kv1.4 Kv 3.4, Kv4.2, Kv 4.3 mRNA↓; Kv1.1, Kv1.2, Kv2.1 Kv 2.2 ↔ mRNA Diabetic Neuropathy (Cao et al., 2010),Whole cell A-current ↓Diabetic neuropathy (Cao et al., 2010; Grabauskas et al., 2011). The gene discussed is KCNB1; the disease is diabetic neuropathy.