To further investigate the mechanism of lncRNA MAFG-AS1 and miR-149-3p in CRC, online analysis software was utilized to predict the relationship between lncRNA MAFG-AS1 and miR-149-3p, the results of which revealed specific binding sites between lncRNA MAFG-AS1 and miR-149-3p (Fig. 3a). The gene discussed is MAFG; the disease is colorectal carcinoma.