Blood biomarkers of vitiligo, including soluble CDs (sCD25, sCD27)6, chemokines (CXCL9, CXCL10)17, S100B11, cytokines (IL-1β, IL-10, IL-17)18,19, and homocysteine20, have been reported to be related to the occurrence and activity of vitiligo. The gene discussed is IL17A; the disease is vitiligo.